News related to Science, Technology, Environment, Agriculture and Medicine in India

Tag: National Institute of Immunology

Inflammatory Bowel Disease: A new therapeutic target

The causative mechanism behind inflammatory bowel disorder is not yet known. The therapeutic strategy to counter the inflammatory response targeted the pathway that was recognised earlier. But there is another pathway that influences inflammation. Soumen Basak’s lab at NII pry apart the role of the two pathways in inflammation. Alvina Deka reports:

Treating Hyperpigmentation: Targeting Fatty Acid Synthesis

Hyperpigmentation, where parts of the skin are darker, pose psycho-social difficulties for some. Indian scientists trace the causative roots of the problem to fatty acid metabolism. Their results point at possible therapeutic interventions. Tanya Jain reports:

Fighting Leishmania with Synthetic Glycoside 

A glycoprotein protects leishmania parasites from digestion by our macrophages. So the parasites can hitch a ride on macrophages to viscera, mucosa or skin and start dividing, causing leishmaniosis. Indian scientists have come up with a synthetic glycoside which targets the glycoprotein and effectively kills the parasites. Tanya Jain, NII, reports.

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